Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511005 | 0.90 | OPRK1 (0.54) | OPRK1OPRM1ALDH1A1HRH3MEN1 | |
| SCHEMBL11510131 | 0.88 | CHRNB2 (0.42) | OPRK1OPRM1FFAR1MAPTMEN1 | |
| SCHEMBL11509371 | 0.87 | OPRM1 (0.43) | OPRK1OPRM1OPRD1FFAR1ALDH1A1 | |
| SCHEMBL11511487 | 0.83 | OPRK1 (0.46) | OPRK1OPRM1OPRD1FFAR1ALDH1A1 | |
| SCHEMBL11510687 | 0.80 | OPRK1 (0.47) | OPRK1OPRM1OPRD1FFAR1ALDH1A1 | |
| SCHEMBL11510335 | 0.79 | FFAR1 (0.54) | OPRK1OPRM1OPRD1FFAR1MEN1 | |
| SCHEMBL3572634 | 0.77 | DRD2 (0.41) | — | |
| SCHEMBL3567045 | 0.77 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL11510979 | 0.77 | PARP14 (0.40) | OPRK1OPRM1ALDH1A1MEN1KMT2A | |
| SCHEMBL11511351 | 0.76 | CHRNB2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161529-A | Phenoxy phenyl pyrrolidine compounds, compositions and methods of use | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-07-17 | — | — | US | disclosed |