Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511489 | 0.82 | NPC1 (0.44) | LMNAPOLBTSHRTP53ALDH1A1 | |
| SCHEMBL22945007 | 0.74 | ALDH1A1 (0.59) | LMNAPOLBTSHRALDH1A1KMT2A | |
| SCHEMBL11367382 | 0.68 | NPC1 (0.49) | LMNAPOLBTSHRTP53ALDH1A1 | |
| SCHEMBL22497309 | 0.67 | LMNA (0.43) | LMNAPOLBTSHRTP53ALDH1A1 | |
| SCHEMBL22497308 | 0.67 | LMNA (0.43) | LMNAPOLBTSHRTP53ALDH1A1 | |
| SCHEMBL23294109 | 0.63 | POLB (0.42) | LMNAPOLBTSHRTP53ALDH1A1 | |
| SCHEMBL11634052 | 0.62 | ALDH1A1 (0.73) | LMNAPOLBTSHRALDH1A1ALOX15 | |
| SCHEMBL6406874 | 0.60 | LMNA (0.65) | LMNATSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL4197148 | 0.60 | NPC1 (0.81) | LMNAPOLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL6403164 | 0.60 | LMNA (0.65) | LMNAPOLBTSHRTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |