Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | PDE6D | O43924 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6411912 | 0.88 | OPRK1 (0.64) | LMNAPDE6DALDH1A1TSHRNPC1 | |
| SCHEMBL6406874 | 0.87 | LMNA (0.65) | LMNAALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL6408118 | 0.84 | L3MBTL1 (0.67) | LMNAPDE6DALDH1A1TSHRNPC1 | |
| SCHEMBL6404093 | 0.83 | TSHR (0.74) | LMNAALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL3915525 | 0.83 | ALDH1A1 (0.67) | LMNAALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL4735710 | 0.82 | ALDH1A1 (0.71) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL9504656 | 0.80 | KDM4E (0.60) | LMNAALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL11510029 | 0.80 | ALDH1A1 (0.52) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4204712 | 0.79 | MEN1 (0.72) | LMNAALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL28480818 | 0.78 | PDE6D (0.71) | PDE6DALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | LMNA 4116/4885PDE6D 3331/4885ALDH1A1 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.