Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11510326 | 0.99 | FFAR1 (0.51) | FFAR1OPRK1OPRM1LTA4HMEN1 | |
| SCHEMBL11511099 | 0.89 | LTA4H (0.63) | FFAR1OPRK1OPRM1LTA4H | |
| SCHEMBL11509496 | 0.89 | OPRK1 (0.62) | FFAR1OPRK1OPRM1LTA4HMEN1 | |
| SCHEMBL11510335 | 0.89 | FFAR1 (0.54) | FFAR1OPRK1OPRM1LTA4HMEN1 | |
| SCHEMBL11511303 | 0.88 | PARP14 (0.48) | FFAR1OPRK1OPRM1LTA4HMEN1 | |
| SCHEMBL11512490 | 0.85 | MEN1 (0.48) | FFAR1OPRK1OPRM1MEN1KMT2A | |
| SCHEMBL11509424 | 0.83 | CHRNB2 (0.46) | FFAR1OPRK1OPRM1LTA4HMEN1 | |
| SCHEMBL11511335 | 0.83 | CHRNB2 (0.49) | FFAR1OPRK1OPRM1LTA4HMEN1 | |
| SCHEMBL11511479 | 0.82 | FFAR1 (0.45) | FFAR1LTA4HMEN1KMT2AHPGD | |
| SCHEMBL6092369 | 0.82 | KDM4E (0.58) | OPRK1OPRM1LTA4HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161529-A | Phenoxy phenyl pyrrolidine compounds, compositions and methods of use | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-07-17 | — | — | US | claimed |
| US-4161529-A | Phenoxy phenyl pyrrolidine compounds, compositions and methods of use | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-07-17 | — | — | US | disclosed |