Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | AR | P10275 | 2/20 | 0.66 |
| ▸ | SHBG | P04278 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | HRH2 | P25021 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512237 | 1.00 | LMNA (0.74) | LMNANR3C1MEN1KMT2AHIF1A | |
| SCHEMBL6566539 | 0.90 | CYP19A1 (0.61) | LMNANR3C1MEN1KMT2AHIF1A | |
| SCHEMBL6566545 | 0.90 | CYP19A1 (0.61) | LMNANR3C1MEN1KMT2AHIF1A | |
| SCHEMBL37494 | 0.85 | LMNA (1.00) | LMNANR3C1MEN1KMT2AHIF1A | |
| SCHEMBL22761988 | 0.85 | LMNA (1.00) | LMNANR3C1MEN1KMT2AHIF1A | |
| SCHEMBL4877448 | 0.85 | LMNA (1.00) | LMNANR3C1MEN1KMT2AHIF1A | |
| SCHEMBL13069287 | 0.85 | LMNA (1.00) | LMNANR3C1MEN1KMT2AHIF1A | |
| SCHEMBL15445000 | 0.85 | LMNA (1.00) | LMNANR3C1MEN1KMT2AHIF1A | |
| SCHEMBL27035399 | 0.85 | LMNA (1.00) | LMNANR3C1MEN1KMT2AHIF1A | |
| SCHEMBL9221947 | 0.84 | SERPINA6 (0.80) | LMNANR3C1MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177269-A | ANTITUMOR AGENTS | AKTIEBOLAGET LEO (SE) | 1979-12-04 | — | — | US | disclosed |