Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513073 | 0.86 | ATM (0.48) | ATMKMT2ATSHRALDH1A1HPGD | |
| SCHEMBL11513322 | 0.85 | ATM (0.47) | ATMKMT2ATSHRALDH1A1HPGD | |
| SCHEMBL11512462 | 0.81 | AKT1 (0.43) | KMT2AGAANPC1RAB9AMEN1 | |
| SCHEMBL11513014 | 0.78 | PTGES (0.41) | ATMKMT2ATSHRALDH1A1HPGD | |
| SCHEMBL11513320 | 0.74 | PTGES (0.42) | ATMKMT2ATSHRALDH1A1HPGD | |
| SCHEMBL11513021 | 0.73 | MMP1 (0.39) | ATMKMT2AALDH1A1HPGDGAA | |
| SCHEMBL11514111 | 0.72 | RAB9A (0.44) | TSHRALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL11512832 | 0.71 | ALDH1A1 (0.44) | KMT2AALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL4700005 | 0.70 | SMN1; SMN2 (0.57) | ATMKMT2ATSHRALDH1A1GAA | |
| SCHEMBL11515773 | 0.70 | ALDH1A1 (0.43) | KMT2AALDH1A1GAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175200-A | N,N-Disubstituted sulfonyl hydrazines | UNIROYAL, INC. (US) | 1979-11-20 | — | — | US | disclosed |