SCHEMBL11514909

SCHEMBL11514909

CP(=O)(CCC(=O)OCCCl)OCCCl

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
ADRA2A P08913 1/20 0.34
ADRA1A P35348 1/20 0.34
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
DGKA P23743 1/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516664 0.81 ALDH1A1 (0.41) ALDH1A1
SCHEMBL11452389 0.81 ALDH1A1 (0.41) ALDH1A1ADRA2AADRA1AMAPTBLM
SCHEMBL5405045 0.80 MGLL (0.37) ADRA2AADRA1AMAPTBLMDGKA
Ethylene Glycol SCHEMBL5407446 0.79 MGLL (0.36) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL6429626 0.77 DGKA (0.47) ALDH1A1DGKA
SCHEMBL11861591 0.76 ALDH1A1 (0.40) ALDH1A1
SCHEMBL11399062 0.76 ALDH1A1 (0.52) ALDH1A1
SCHEMBL9601098 0.73 ADRA2A (0.50) ALDH1A1ADRA2AADRA1AMAPTBLM
SCHEMBL11025207 0.72 CYP1A2 (0.44) ALDH1A1
SCHEMBL11515298 0.70 SMN1; SMN2 (0.45) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4179483-A 2-Chloroethyl phosphonates MONSANTO COMPANY (US) 1979-12-18 US claimed
US-4179483-A 2-Chloroethyl phosphonates MONSANTO COMPANY (US) 1979-12-18 US disclosed