Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924931 | 0.84 | LDHA (0.45) | LDHAPSMB8HSD17B10MAPTRAB9A | |
| SCHEMBL27328869 | 0.84 | LDHA (0.45) | LDHAPSMB8HSD17B10MAPTRAB9A | |
| SCHEMBL13646896 | 0.81 | MAPT (0.56) | LDHAPSMB8MAPTRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11513903 | 0.75 | INSR (0.40) | LDHAPSMB8MAPTRAB9AALDH1A1 | |
| SCHEMBL11937029 | 0.73 | SMN1; SMN2 (0.45) | HSD17B10MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL12278579 | 0.72 | LDHA (0.57) | LDHAPSMB8MAPTRAB9AALDH1A1 | |
| Iodide SCHEMBL4019399 | 0.71 | KDM4E (0.51) | LDHAPSMB8MAPTRAB9AALDH1A1 | |
| Iodide SCHEMBL31063723 | 0.70 | MAPT (0.61) | MAPTRAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL28124654 | 0.69 | KDM4E (0.55) | LDHAPSMB8MAPTRAB9AALDH1A1 | |
| SCHEMBL4869324 | 0.68 | KDM4E (0.54) | LDHAPSMB8MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145537-A | BENZOTHIAZOLIUM DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |