Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10482945 | 0.83 | KDM4E (0.45) | KDM4EMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL1191220 | 0.80 | CA2 (0.44) | KDM4EMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL6987504 | 0.78 | F2 (0.34) | KDM4EMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL8979738 | 0.78 | CYP3A4 (0.38) | KDM4EMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL3980869 | 0.77 | CES2 (0.37) | MAPTHSD17B10TSHRALDH1A1PIM1 | |
| SCHEMBL10822473 | 0.77 | PARP1 (0.35) | KDM4EMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL27989848 | 0.74 | GAA (0.36) | KDM4EHSD17B10TSHRALDH1A1HPGD | |
| SCHEMBL7471896 | 0.74 | CA1 (0.53) | KDM4EMAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL2934781 | 0.74 | ALDH1A1 (0.48) | KDM4EMAPTTSHRALDH1A1HPGD | |
| SCHEMBL17977340 | 0.72 | MAOB (0.38) | ALDH1A1HPGDL3MBTL1PARP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137325-A | Antisecretory oxamic acid esters | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-01-30 | — | — | US | claimed |
| CN-1104192-C | Process for producing pesticidal composition | HOECHST SCHERING AGREVO GMBH (DE) | 2003-04-02 | — | — | CN | disclosed |
| CN-1146710-A | Method for producing pesticide composition | HOECHST SCHERING AGREVO GMBH (DE) | 1997-04-02 | — | — | CN | disclosed |
| US-4161530-A | CYCLIC SUBSTITUTED AMINO ALCOHOL BETA-RECEPTOR-BLOCKING AGENT AND TRYPTOPHANE | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-4137325-A | Antisecretory oxamic acid esters | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |