Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.64 |
| ▸ | PPARA | Q07869 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657593 | 0.94 | LMNA (0.72) | LMNADNMT3APPARAHPGDALDH1A1 | |
| SCHEMBL11356211 | 0.88 | LMNA (0.64) | LMNADNMT3APPARAHPGDHDAC1 | |
| SCHEMBL11464602 | 0.88 | PTGER4 (0.69) | LMNADNMT3APPARAHPGDALDH1A1 | |
| SCHEMBL17339437 | 0.87 | LMNA (0.62) | LMNADNMT3APPARAHPGDALDH1A1 | |
| SCHEMBL29617795 | 0.87 | LMNA (0.62) | LMNADNMT3APPARAHPGDALDH1A1 | |
| SCHEMBL11706059 | 0.87 | DNMT3A (0.72) | LMNADNMT3APPARAHPGDHDAC1 | |
| SCHEMBL8261934 | 0.87 | DNMT3A (0.84) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11488803 | 0.86 | PPARA (0.67) | LMNADNMT3APPARAHDAC1HDAC6 | |
| SCHEMBL11445605 | 0.85 | LMNA (0.60) | LMNADNMT3APPARAHPGDMAPT | |
| SCHEMBL14507293 | 0.85 | LMNA (0.60) | LMNADNMT3APPARAALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |