Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PPARA | Q07869 | 1/20 | 0.62 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657593 | 0.91 | LMNA (0.72) | LMNAPPARADNMT3AHDAC1HDAC6 | |
| SCHEMBL11516368 | 0.88 | LMNA (0.68) | LMNAPPARADNMT3AHDAC1HDAC6 | |
| Meglitinide SCHEMBL29829482 | 0.88 | DNMT3A (0.78) | DNMT3AHDAC1HDAC6NLRP3 | |
| Meglitinide SCHEMBL37926 | 0.88 | DNMT3A (0.78) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11356211 | 0.88 | LMNA (0.64) | PTGER4LMNAPPARADNMT3AHDAC1 | |
| SCHEMBL14507293 | 0.87 | LMNA (0.60) | PTGER4LMNAPPARADNMT3AHDAC1 | |
| SCHEMBL2242766 | 0.85 | PTGER4 (0.66) | PTGER4NR1H4LMNAEPHX2ALDH1A1 | |
| SCHEMBL11488803 | 0.85 | PPARA (0.67) | LMNAPPARADNMT3AHDAC1HDAC6 | |
| SCHEMBL11445600 | 0.85 | LMNA (0.63) | LMNAPPARADNMT3AHDAC1HDAC6 | |
| SCHEMBL11469323 | 0.85 | POLB (0.67) | PTGER4NR1H4PPARAEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221815-A | HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-09-09 | — | — | US | disclosed |