SCHEMBL11516655

SCHEMBL11516655

[O-][S+]1c2ccccc2Cc2cc(Cl)ccc21.[O-][S+]1c2ccccc2Cc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
AHR P35869 1/20 0.33
CYP2A6 P11509 1/20 0.32
DRD2 P14416 3/20 0.32
DRD4 P21917 3/20 0.32
CYP1A2 P05177 1/20 0.32
HSD17B3 P37058 1/20 0.32
METAP1 P53582 1/20 0.32
HTT P42858 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ITGA1 P56199 1/20 0.31
ACHE P22303 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37076 1.00 CA1 (0.33) CA1CA2CA4CA6HPGD
SCHEMBL6070128 0.91 AHR (0.37) CA1CA2CA4CA6AHR
Anthraquinone SCHEMBL9789080 0.89 MAOA (0.43) HPGDL3MBTL1CYP1A2METAP1ALDH1A1
SCHEMBL1155668 0.89 DRD2 (0.35) CA1CA2CA4CA6HPGD
9,10-Phenanthrenequinone SCHEMBL11210917 0.88 S100A4 (0.49) HPGDL3MBTL1METAP1HTTITGA1
SCHEMBL15281929 0.87 CHRM2 (0.32) DRD2DRD4
SCHEMBL11751062 0.86 HTT (0.39) AHRCYP2A6DRD2DRD4CYP1A2
SCHEMBL6070528 0.83 CYP1A2 (0.42) CYP1A2HSD17B3HTTALDH1A1
SCHEMBL1821431 0.83 LPAR1 (0.31)
SCHEMBL9160477 0.82 MAOA (0.39) HPGDCYP2A6DRD2DRD4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4134811-A Halogenated photopolymerizable compositions UCB, SOCIETE ANONYME (BE) 1979-01-16 US disclosed