Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614828 | 0.85 | TDP2 (0.38) | HSD17B3TDP2ESR2KDM4EALDH1A1 | |
| SCHEMBL6070128 | 0.85 | AHR (0.37) | PGRHTT | |
| SCHEMBL37076 | 0.83 | CA1 (0.33) | CYP1A2HSD17B3ALDH1A1HTT | |
| SCHEMBL11516655 | 0.83 | CA1 (0.33) | CYP1A2HSD17B3ALDH1A1HTT | |
| Anthraquinone SCHEMBL9789080 | 0.75 | MAOA (0.43) | CYP1A2ALDH1A1MEN1KMT2A | |
| 9,10-Phenanthrenequinone SCHEMBL11210917 | 0.74 | S100A4 (0.49) | DHODHTDP2KDM4EPOLBHTT | |
| SCHEMBL1155668 | 0.73 | DRD2 (0.35) | CYP1A2HSD17B3 | |
| SCHEMBL11751062 | 0.73 | HTT (0.39) | CYP1A2HSD17B3KDM4EALDH1A1HTT | |
| SCHEMBL15281929 | 0.73 | CHRM2 (0.32) | — | |
| SCHEMBL472580 | 0.72 | AHR (0.36) | TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7126011-B2 | Reacting 2-chlorothiobenzoyl chloride with aromatic compound; drug for psychological disorder therapy; photopolymerization sensitizer | PROM LIMITED (GB) | 2006-10-24 | — | — | US | disclosed |
| US-20030229233-A1 | Process for the preparation of thioxanthones | PROM LIMITED (GB) | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229233-A1 | Process for the preparation of thioxanthones | TST, TPST2, SULT2A1 | CYP1A2 70/4885DHODH 1429/4885HSD17B3 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.