Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.60 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494187 | 0.87 | ADORA2B (0.69) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL11518501 | 0.83 | ADORA2B (0.70) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL11409631 | 0.83 | ADORA2B (0.70) | ADORA3ADORA1ADORA2AADORA2BDOT1L | |
| SCHEMBL11409612 | 0.83 | ADORA2B (0.70) | ADORA3ADORA1ADORA2AADORA2BDOT1L | |
| SCHEMBL11415994 | 0.82 | ADORA2B (0.69) | ADORA3ADORA1ADORA2AADORA2BDOT1L | |
| SCHEMBL11416011 | 0.82 | ADORA2B (0.69) | ADORA3ADORA1ADORA2AADORA2BDOT1L | |
| SCHEMBL9495200 | 0.79 | ADORA2A (0.73) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL10579997 | 0.77 | ADORA2A (0.67) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL10580014 | 0.77 | ADORA2A (0.67) | ADORA3ADORA1ADORA2AADORA2BRXFP1 | |
| SCHEMBL9493927 | 0.77 | ADORA3 (0.70) | ADORA3ADORA1ADORA2AADORA2BHSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167565-A | Adenosine-5'-carboxamides and method of use | ABBOTT LABORATORIES (US) | 1979-09-11 | — | — | US | disclosed |