Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518579 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL26428802 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL22223310 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL27050808 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL11518693 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL13176551 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL25834780 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL10299251 | 0.95 | SLC22A6 (0.58) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL17992598 | 0.89 | CES2 (0.44) | LMNAMEN1KMT2A | |
| SCHEMBL9973392 | 0.86 | CES2 (0.48) | LMNATSHRNFKB1PMP22MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034927-A1 | AMMONIA PRODUCTION METHOD AND AMMONIA PRODUCTION APPARATUS | 国立大学法人東京大学 | 2022-02-17 | — | — | WO | disclosed |
| WO-2022034928-A1 | AMMONIA PRODUCTION METHOD AND AMMONIA PRODUCTION APPARATUS | 日産化学株式会社 | 2022-02-17 | — | — | WO | disclosed |
| US-20180186755-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20170363637-A1 | Method and Kit for Determining Risk of Preterm Birth and/or Birth of Low-Birth-Weight Baby | HIROSHIMA UNIVERSITY (JP) | 2017-12-21 | — | — | US | disclosed |
| US-9683093-B1 | Resin composition and resin molded article | FUJI XEROX CO., LTD. (JP) | 2017-06-20 | — | — | US | disclosed |
| US-7737287-B2 | Anomeric derivatives of monosaccharides | ALCHEMIA LIMITED (AU) | 2010-06-15 | — | — | US | disclosed |
| US-4154851-A | ANTIDEPRESSANTS, ANTIAGRESSIVE AGENTS | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170363637-A1 | Method and Kit for Determining Risk of Preterm Birth and/or Birth of Low-Birth-Weight Baby | LGALS3, LGALS3BP, LGALS1 | LMNA 144/4885TSHR 2759/4885NFKB1 1365/4885 |
| US-20180186755-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | LMNA 179/4885TSHR 4552/4885NFKB1 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.