Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NMT1 | P30419 | 1/20 | 0.48 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18890669 | 0.78 | TDP1 (0.58) | TDP1POLBTGM2KDM4ENPC1 | |
| SCHEMBL5157140 | 0.77 | TAS2R38 (0.52) | POLBTGM2KDM4ENPC1RAB9A | |
| SCHEMBL1454275 | 0.74 | TDP1 (0.65) | TDP1POLBTGM2KDM4ENPC1 | |
| SCHEMBL9068384 | 0.73 | POLB (0.50) | TDP1POLBTGM2NPC1RAB9A | |
| SCHEMBL18722598 | 0.73 | TGM2 (0.50) | TDP1POLBTGM2KDM4ENPC1 | |
| SCHEMBL455439 | 0.72 | TDP1 (0.70) | TDP1POLBTGM2KDM4ENPC1 | |
| SCHEMBL1276739 | 0.72 | KMT2A (0.79) | TDP1POLBKDM4ENPC1RAB9A | |
| SCHEMBL5705035 | 0.72 | TDP1 (0.56) | TDP1POLBTGM2KDM4ENPC1 | |
| SCHEMBL1275920 | 0.72 | ALDH1A1 (0.70) | TDP1POLBKDM4ENPC1RAB9A | |
| SCHEMBL11410456 | 0.72 | CYP1A2 (0.59) | TDP1POLBKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179469-A | Preparation of amines | UOP INC. (US) | 1979-12-18 | — | — | US | disclosed |