Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416124 | 0.80 | KIF11 (0.55) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL1454275 | 0.76 | TDP1 (0.65) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL6850999 | 0.74 | KDM4E (0.79) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL1276739 | 0.74 | KMT2A (0.79) | TDP1POLBNPC1RAB9AMEN1 | |
| SCHEMBL678436 | 0.74 | TDP1 (0.56) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL11410456 | 0.74 | CYP1A2 (0.59) | TDP1POLBNPC1RAB9AMEN1 | |
| SCHEMBL455439 | 0.74 | TDP1 (0.70) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL1275920 | 0.74 | ALDH1A1 (0.70) | TDP1POLBNPC1RAB9AMEN1 | |
| SCHEMBL4406279 | 0.72 | HSD17B10 (0.55) | TDP1NPC1RAB9AMEN1CYP3A4 | |
| SCHEMBL23607581 | 0.72 | TDP1 (0.54) | TDP1POLBNPC1RAB9AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323714-B1 | 1,3-selenazole derivatives and their use as anticancer drugs or as agrochemicals | PRESIDENT OF GIFU UNIVERSITY (JP) | 2006-09-20 | — | — | EP | disclosed |