Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339687 | 1.00 | MCL1 (0.49) | MCL1ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL2718691 | 0.98 | MCL1 (0.50) | MCL1ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL5770917 | 0.93 | MCL1 (0.43) | MCL1ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL16291203 | 0.81 | MCL1 (0.47) | MCL1ALDH1A1MAPK1KDM4EKMT2A | |
| SCHEMBL535049 | 0.80 | MCL1 (0.46) | MCL1ALDH1A1MAPK1KMT2ACA1 | |
| SCHEMBL535448 | 0.77 | LMNA (0.45) | MCL1ALDH1A1MAPK1LMNAKMT2A | |
| SCHEMBL8984610 | 0.77 | MCL1 (0.44) | MCL1ALDH1A1MAPK1KDM4EKMT2A | |
| SCHEMBL7353241 | 0.77 | MCL1 (0.58) | MCL1MAPK1KDM4EKMT2ACA1 | |
| SCHEMBL8081259 | 0.77 | MCL1 (0.58) | MCL1MAPK1KDM4EKMT2ACA1 | |
| Succinic Acid SCHEMBL3186231 | 0.76 | ALDH1A1 (0.42) | MCL1ALDH1A1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885883-B1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | MITSUBISHI PHARMA CORP (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |