Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | CTSG | P08311 | 2/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | CMA1 | P23946 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961994 | 0.84 | GAA (0.59) | GAAPRSS1CTSGCTRB1CMA1 | |
| Hydrochloric Acid SCHEMBL9331679 | 0.82 | GAA (0.57) | GAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL5655365 | 0.82 | PRSS1 (0.68) | GAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL30539770 | 0.80 | GAA (0.59) | GAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL6084716 | 0.79 | PTPRC (0.62) | GAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL1221369 | 0.79 | RAB9A (0.66) | GAAGLASMN1; SMN2LMNAPOLB | |
| SCHEMBL5531639 | 0.79 | GAA (0.57) | GAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL9149660 | 0.79 | GAA (0.57) | GAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL27785114 | 0.79 | GAA (0.57) | GAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL14219258 | 0.78 | GPR139 (0.55) | GAAPRSS1CTSGCTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162319-A | ANTHELMINTICS, PSYCHOTROPIC, CNS, HYPOGLYCOMIC AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-07-24 | — | — | US | disclosed |
| US-4120961-A | ANTIHELMINTICS, CNS ACITVITY | E. MERCK (DE) | 1978-10-17 | — | — | US | disclosed |
| US-4051243-A | RING SUBSTITUTED PYRAZINO-ISOQUINOLINE DERIVATIVES AND THEIR PREPARATION | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |