Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526454 | 0.79 | ACHE (0.49) | ALDH1A1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL27923637 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL11520585 | 0.76 | HRH3 (0.39) | ALDH1A1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL10286349 | 0.75 | ACHE (0.45) | ALDH1A1KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL11524271 | 0.70 | SIRT1 (0.43) | ALDH1A1KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL11524267 | 0.70 | BDKRB1 (0.39) | ALDH1A1KDM4EMAPTSLC6A2SLC6A4 | |
| SCHEMBL10287027 | 0.68 | ADORA1 (0.39) | ALDH1A1KDM4EMAPTHPGDPDCD1 | |
| SCHEMBL11522413 | 0.67 | P2RX7 (0.34) | ALDH1A1KDM4EMAPTP2RX7RAB9A | |
| SCHEMBL526243 | 0.67 | KDM4E (0.45) | ALDH1A1KDM4EMAPTL3MBTL1SLC6A2 | |
| SCHEMBL10286055 | 0.67 | HRH2 (0.41) | ALDH1A1KDM4EMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160094-A | Tetrahydroquinoline derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |