Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.43 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465928 | 0.80 | UHRF1 (0.37) | SIRT1UHRF1CHRM4CYP1A2HSD17B10 | |
| SCHEMBL527248 | 0.77 | UGT2B17 (0.50) | UHRF1CHRM4CYP1A2HSD17B10KDM4E | |
| SCHEMBL11465929 | 0.77 | ALDH1A1 (0.36) | SIRT1UHRF1CHRM4CYP1A2HSD17B10 | |
| SCHEMBL11522230 | 0.75 | SIRT1 (0.40) | SIRT1HSD17B10KDM4EUSP2HPGD | |
| SCHEMBL10841326 | 0.74 | SIRT1 (0.39) | SIRT1HSD17B10KDM4EUSP2HPGD | |
| SCHEMBL10286333 | 0.72 | UGT2B17 (0.45) | UHRF1CHRM4CYP1A2HSD17B10KDM4E | |
| SCHEMBL11520291 | 0.70 | ALDH1A1 (0.39) | CHRM4KDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL11522468 | 0.70 | SIRT1 (0.36) | SIRT1 | |
| SCHEMBL10286046 | 0.70 | ACHE (0.42) | CYP1A2HSD17B10KDM4EUSP2HPGD | |
| SCHEMBL11730878 | 0.70 | EEF2K (0.39) | SIRT1CYP1A2HSD17B10KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160094-A | Tetrahydroquinoline derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |