Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GHSR | Q92847 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522456 | 0.92 | KDM4E (0.51) | MAPTGHSRNPC1KDM4EALDH1A1 | |
| SCHEMBL11520937 | 0.86 | MAPT (0.48) | MAPTGHSRNPC1KDM4EALDH1A1 | |
| SCHEMBL11522459 | 0.82 | MAPT (0.47) | MAPTGHSRNPC1KDM4EALDH1A1 | |
| SCHEMBL11398748 | 0.80 | NPC1 (0.55) | MAPTGHSRNPC1KDM4EALDH1A1 | |
| SCHEMBL11527031 | 0.80 | NPC1 (0.41) | MAPTGHSRNPC1KDM4EALDH1A1 | |
| SCHEMBL11522756 | 0.77 | KDM4E (0.48) | MAPTNPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL11523922 | 0.77 | RAF1 (0.43) | MAPTNPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL11521872 | 0.77 | KDM4E (0.40) | MAPTNPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL11179749 | 0.76 | MAPT (0.52) | MAPTGHSRNPC1KDM4EALDH1A1 | |
| SCHEMBL11524573 | 0.76 | RAB9A (0.46) | MAPTGHSRNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |