Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521954 | 0.81 | TYK2 (0.44) | KDM4ENPC1ALDH1A1MAPK1TYK2 | |
| SCHEMBL11523665 | 0.80 | HCRTR1 (0.48) | KDM4ENPC1ALDH1A1MAPK1TYK2 | |
| SCHEMBL11527031 | 0.80 | NPC1 (0.41) | KDM4ENPC1ALDH1A1MAPK1TYK2 | |
| SCHEMBL11522456 | 0.79 | KDM4E (0.51) | KDM4ENPC1ALDH1A1MAPK1KMT2A | |
| SCHEMBL11524635 | 0.78 | TYK2 (0.43) | KDM4ENPC1ALDH1A1MAPK1TYK2 | |
| SCHEMBL11524682 | 0.78 | TYK2 (0.41) | KDM4ENPC1ALDH1A1MAPK1TYK2 | |
| SCHEMBL11520929 | 0.77 | MAPT (0.51) | KDM4ENPC1ALDH1A1MAPK1TYK2 | |
| SCHEMBL11519411 | 0.76 | RAB9A (0.47) | KDM4ENPC1TYK2RAB9AMAPT | |
| SCHEMBL8657584 | 0.75 | RAB9A (0.57) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL11398829 | 0.74 | GAA (0.52) | KDM4ENPC1ALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |