Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521872 | 0.87 | KDM4E (0.40) | RAF1RAB9ANPC1GRM5MEN1 | |
| SCHEMBL11526513 | 0.79 | RAB9A (0.40) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11520929 | 0.77 | MAPT (0.51) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11522456 | 0.72 | KDM4E (0.51) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11527031 | 0.71 | NPC1 (0.41) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11521631 | 0.71 | WNT3A (0.45) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL11524059 | 0.69 | TRPV1 (0.42) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL11523923 | 0.68 | RAB9A (0.43) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL11521970 | 0.68 | ALDH1A1 (0.41) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL11527118 | 0.67 | STIM1 (0.42) | RAB9ANPC1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |