Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | METAP1 | P53582 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423421 | 0.86 | METAP1 (0.74) | SIGMAR1HTR1AMETAP1ACHEMC4R | |
| Hydrochloric Acid SCHEMBL29583950 | 0.84 | METAP1 (0.74) | SIGMAR1HTR1AMETAP1ACHEMC4R | |
| SCHEMBL7260605 | 0.82 | CYP26A1 (0.47) | SIGMAR1HTR1AACHEDRD2HTR2A | |
| SCHEMBL6492064 | 0.81 | SIGMAR1 (0.70) | SIGMAR1HTR1AMETAP1ACHEMC4R | |
| SCHEMBL5356984 | 0.79 | METAP1 (0.72) | SIGMAR1HTR1AMETAP1ACHEDRD2 | |
| SCHEMBL11522306 | 0.78 | SIGMAR1 (0.68) | SIGMAR1HTR1AMETAP1ACHEMC4R | |
| SCHEMBL11727341 | 0.77 | SIGMAR1 (0.63) | SIGMAR1HTR1AMETAP1ACHEMC4R | |
| Hydrochloric Acid SCHEMBL11736949 | 0.76 | SIGMAR1 (0.62) | SIGMAR1HTR1AMETAP1ACHEMC4R | |
| SCHEMBL27014166 | 0.75 | ACHE (0.45) | SIGMAR1HTR1AACHEDRD2HTR2A | |
| SCHEMBL9344339 | 0.75 | LMNA (0.54) | SIGMAR1HTR1AACHEHTR2CCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1736381-B | Use of morpholine methyltetralone in preparation of smooth muscles spasmolytic | UNIV SHENYANG PHARMACEUTICAL | 2010-09-08 | — | — | CN | disclosed |
| CN-1736381-A | Use of morpholine methyltetralone in preparation of smooth muscles spasmolytic | UNIV SHENYANG PHARMACEUTICAL (CN) | 2006-02-22 | — | — | CN | disclosed |