Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | CTSS | P25774 | 4/20 | 0.56 |
| ▸ | REN | P00797 | 7/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525633 | 1.00 | PPARA (0.64) | PPARAPPARGCTSSRENCTSK | |
| SCHEMBL11522829 | 1.00 | PPARA (0.64) | PPARAPPARGCTSSRENCTSK | |
| SCHEMBL11505366 | 0.92 | PPARA (0.68) | PPARAPPARGCTSSRENACE | |
| SCHEMBL3820032 | 0.83 | PPARA (0.76) | PPARAPPARGCTSSRENCTSK | |
| SCHEMBL17051 | 0.83 | PPARA (0.90) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL828674 | 0.83 | PPARA (0.90) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL1132901 | 0.83 | PPARA (0.90) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL16576480 | 0.81 | CTSS (0.66) | PPARAPPARGCTSSRENCTSK | |
| SCHEMBL29787684 | 0.81 | PPARA (0.52) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL29556874 | 0.81 | PPARA (0.75) | PPARAPPARGCTSSRENCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133805-A | INHIBIT RELEASE OR PITUITARY GROWTH HORMONE, GLUCAGON, AND INSULIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |