Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520329 | 0.82 | APP (0.56) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11566254 | 0.81 | KMO (0.48) | APPMAPTMEN1KMT2AACHE | |
| SCHEMBL11520999 | 0.80 | APP (0.57) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11521568 | 0.79 | APP (0.53) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11521948 | 0.79 | APP (0.60) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7140685 | 0.76 | MAPT (0.65) | MAPTMEN1KMT2AACHEHSD17B10 | |
| SCHEMBL11521075 | 0.73 | HSP90AA1 (0.46) | APPMAPTMEN1KMT2ATSHR | |
| SCHEMBL6577902 | 0.70 | ACHE (0.75) | MAPTMEN1KMT2AACHEHSD17B10 | |
| SCHEMBL11520089 | 0.68 | HSP90AA1 (0.48) | APPMAPTMEN1KMT2ATSHR | |
| SCHEMBL4163474 | 0.68 | MAPT (0.79) | MAPTMEN1KMT2AACHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |