Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521655 | 0.83 | RAB9A (0.39) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL11523266 | 0.78 | RAB9A (0.45) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL11526513 | 0.77 | RAB9A (0.40) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL11523410 | 0.75 | CHEK1 (0.54) | CHEK1 | |
| SCHEMBL11521485 | 0.74 | MAPT (0.42) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11373756 | 0.73 | PYGL (0.42) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11525162 | 0.73 | MEN1 (0.43) | NPC1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL11522663 | 0.72 | RAB9A (0.42) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL11524038 | 0.71 | RAB9A (0.41) | RAB9ANPC1PPIAITGB1POLB | |
| SCHEMBL11519925 | 0.70 | TYK2 (0.46) | RAB9ANPC1PPIAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |