Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 3/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523922 | 0.79 | RAF1 (0.43) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL11523266 | 0.78 | RAB9A (0.45) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL11523894 | 0.77 | RAB9A (0.40) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL11522456 | 0.76 | KDM4E (0.51) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL11520929 | 0.75 | MAPT (0.51) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL11523410 | 0.75 | CHEK1 (0.54) | KDR | |
| SCHEMBL11521872 | 0.74 | KDM4E (0.40) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL11521485 | 0.74 | MAPT (0.42) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11521655 | 0.74 | RAB9A (0.39) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL11522663 | 0.72 | RAB9A (0.42) | RAB9ANPC1MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |