Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370935 | 0.78 | HTT (0.49) | AGTR1HTR6KDM4EAKR1B1HTT | |
| SCHEMBL11480360 | 0.76 | KDM4E (0.58) | HTR6KDM4ELMNANAMPT | |
| SCHEMBL10834173 | 0.73 | AGTR1 (0.65) | AGTR1HTR6KDM4EAKR1B1HTT | |
| SCHEMBL13506044 | 0.72 | HTR6 (0.48) | AGTR1HTR6KDM4EAKR1B1SMN1; SMN2 | |
| SCHEMBL27869139 | 0.70 | HTR6 (0.46) | AGTR1HTR6KDM4EAKR1B1SMN1; SMN2 | |
| SCHEMBL27767382 | 0.70 | HTT (0.76) | AGTR1HTR6KDM4EAKR1B1HTT | |
| SCHEMBL3377180 | 0.70 | PKM (0.59) | AGTR1HTR6KDM4EAKR1B1HTT | |
| SCHEMBL29277557 | 0.70 | AGTR1 (0.49) | AGTR1HTR6KDM4EAKR1B1HTT | |
| SCHEMBL6943431 | 0.70 | CYP11B1 (0.57) | AGTR1HTR6KDM4EAKR1B1HTT | |
| SCHEMBL4653156 | 0.70 | AGTR1 (0.57) | AGTR1HTR6KDM4EAKR1B1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |