Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521631 | 0.80 | WNT3A (0.45) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11381369 | 0.79 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL11521970 | 0.78 | ALDH1A1 (0.41) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11398079 | 0.75 | KDR (0.49) | RAB9AMEN1KMT2AATMMAPT | |
| SCHEMBL11525072 | 0.74 | RAB9A (0.40) | RAB9ANPC1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11527118 | 0.73 | STIM1 (0.42) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11521872 | 0.70 | KDM4E (0.40) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11520914 | 0.69 | GRM4 (0.39) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11523852 | 0.68 | ATR (0.45) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL11523922 | 0.68 | RAF1 (0.43) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |