Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | OGA | O60502 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523341 | 0.77 | MTOR (0.41) | CYP3A4CYP2D6MAPK1RAB9AMEN1 | |
| SCHEMBL11522959 | 0.75 | UGT2B7 (0.43) | CYP1A2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL4855596 | 0.75 | RAB9A (0.52) | RAB9AMEN1KMT2AHTTNPC1 | |
| SCHEMBL9788832 | 0.74 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2D6CYP2C9MAPK1 | |
| SCHEMBL477457 | 0.72 | MAPK1 (0.57) | CYP1A2CYP3A4CYP2D6CYP2C9MAPK1 | |
| SCHEMBL11525863 | 0.71 | LMNA (0.50) | CYP3A4CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL11524159 | 0.71 | CNR1 (0.47) | MEN1KMT2A | |
| SCHEMBL11526264 | 0.69 | SLC6A4 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C9MAPK1 | |
| SCHEMBL11525667 | 0.68 | ALDH1A1 (0.42) | MAPK1RAB9AMEN1KMT2AHTT | |
| SCHEMBL10264576 | 0.68 | MEN1 (0.51) | CYP1A2CYP3A4CYP2D6CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147780-A | α-Amino-phosphonous acids for inhibiting bacteria and yeast | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |