Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12774634 | 0.91 | MMP8 (0.40) | HTTMMP8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6807017 | 0.82 | MMP8 (0.41) | MMP8SLC7A5CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27515050 | 0.81 | LOXL2 (0.41) | ALDH1A1MIF | |
| SCHEMBL8794058 | 0.79 | TAS1R3 (0.39) | TAS1R3TAS1R1MMP8NLRP3SMN1; SMN2 | |
| SCHEMBL6806730 | 0.79 | ALOX15 (0.35) | HTTNPSR1SLC7A5CYP1A2SMN1; SMN2 | |
| SCHEMBL3151639 | 0.79 | SRC (0.41) | HTTNPSR1SLC7A5SMN1; SMN2ALDH1A1 | |
| SCHEMBL27224323 | 0.78 | SMN1; SMN2 (0.38) | TAS1R3TAS1R1HTTNPSR1NLRP3 | |
| SCHEMBL6808060 | 0.78 | HTT (0.43) | HTTNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7486568 | 0.77 | MAPK1 (0.43) | TAS1R3TAS1R1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12898688 | 0.76 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239468-A | Preparation method of 2- (2, 6-diethyl-4-methylphenyl) -malonic acid dimethyl ester | 上海工程技术大学 | 2023-06-09 | — | — | CN | claimed |
| CN-118184600-A | Preparation method and application of [1,4,5] oxydiazepane | 上海农帆生物科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117326976-A | Synthesis method of 2, 6-diethyl-4-methylbenzene malononitrile | 中国科学院大连化学物理研究所 | 2024-01-02 | — | — | CN | disclosed |
| CN-116239468-A | Preparation method of 2- (2, 6-diethyl-4-methylphenyl) -malonic acid dimethyl ester | 上海工程技术大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-116239468-A | Preparation method of 2- (2, 6-diethyl-4-methylphenyl) -malonic acid dimethyl ester | 上海工程技术大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-116239468-A | Preparation method of 2- (2, 6-diethyl-4-methylphenyl) -malonic acid dimethyl ester | 上海工程技术大学 | 2023-06-09 | — | — | CN | disclosed |
| EP-3564208-B1 | METHOD FOR PREPARING 2-(CYCLOHEXENYLENE) MALONIC ACID DERIVATIVE AND USE THEREOF | ORIENTAL LUZHOU AGROCHEMICALS CO LTD (CN) | 2021-11-10 | — | — | EP | disclosed |
| CN-113321583-A | Preparation method and application of 2, 6-diethyl-4-methyl phenyl malonic acid diester | 利尔化学股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| US-10836777-B2 | Method for preparing 2-(cyclohexenylidene) malonic acid derivatives and uses thereof | ORIENTAL(LUZHOU) AGROCHEMICALS. CO., LTD (CN) | 2020-11-17 | — | — | US | disclosed |
| CN-108264469-B | Method for preparing 2- (cyclohexenylene) malonic acid derivative and application thereof | 泸州东方农化有限公司 | 2020-07-10 | — | — | CN | disclosed |
| US-7915199-B1 | Herbicidal composition | SYNGENTA CROP PROTECTION, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-7605111-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7605111-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7459414-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-7459414-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | MAETZKE THOMAS (CH) | 2004-10-07 | — | — | US | disclosed |
| EP-1183317-B1 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6552187-B1 | Cyclization condensation of arylmalonic acid diamides or arylmalonic acid monoamides with hydrazine derivatives forming substituted 3-hydroxy-4-aryl-5-oxopyrazolines; high yield and purity | SYNGENTA CROP PROTECTION, INC. | 2003-04-22 | — | — | US | disclosed |
| EP-1183317-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | Syngenta Participations AG (CH) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000078881-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836777-B2 | Method for preparing 2-(cyclohexenylidene) malonic acid derivatives and uses thereof | ME1, HPD, PIN4 | TAS1R3 4597/4885TAS1R1 4730/4885HTT 1671/4885 |
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | CBR3, CBR1, CYC1 | TAS1R3 1544/4885TAS1R1 1771/4885HTT 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.