Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 13/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393216 | 0.95 | MAPT (0.39) | MAPTPIM1PIM3JAK2TP53 | |
| SCHEMBL2935664 | 0.79 | KIF11 (0.44) | MAPTPIM1PIM3JAK2TP53 | |
| Carbazole SCHEMBL738564 | 0.76 | PTGS1 (0.47) | MAPTKDM4EMEN1LMNAMPO | |
| Carbazole SCHEMBL7710915 | 0.76 | PTGS1 (0.47) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL11537835 | 0.75 | KIF11 (0.45) | MAPTPIM1PIM3JAK2TP53 | |
| SCHEMBL29001995 | 0.74 | KIF11 (0.44) | MAPTPIM1PIM3JAK2TP53 | |
| SCHEMBL27500727 | 0.74 | PARP14 (0.49) | MAPTPIM1PIM3JAK2TP53 | |
| SCHEMBL3924071 | 0.73 | PARP14 (0.50) | MAPTJAK2TP53HTTKLK7 | |
| SCHEMBL27747315 | 0.73 | ERAP1 (0.46) | MAPTPARP14ERAP1KIF11KDM4E | |
| SCHEMBL15560416 | 0.72 | KIF11 (0.47) | MAPTPIM1PIM3JAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115349018-A | Novel L-rhamnose isomerase | 国立大学法人香川大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-112980731-B | L-xylulose producing strain and application thereof | 南京工业大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-112980731-A | L-xylulose producing strain and application thereof | 南京工业大学 | 2021-06-18 | — | — | CN | disclosed |
| US-4170696-A | PHENOL-FORMALDEHYDE OR CROSSLINKED POLYSTYRENE WITH DIETHYLAMINOETHYL GROUPS, ION EXCHANGE RESINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-10-09 | — | — | US | disclosed |