Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.39 |
| ▸ | TEK | Q02763 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522661 | 0.88 | IL2 (0.42) | RAB9AMAPTNPC1ALDH1A1L3MBTL1 | |
| SCHEMBL11385328 | 0.88 | RAB9A (0.47) | RAB9AMAPTNPSR1NPC1ALDH1A1 | |
| SCHEMBL11521149 | 0.86 | NPC1 (0.46) | RAB9AMAPTNPC1IL2SMN1; SMN2 | |
| SCHEMBL11604630 | 0.86 | RAB9A (0.48) | RAB9AMAPTNPC1CNR1JAK2 | |
| SCHEMBL11519534 | 0.85 | RAB9A (0.40) | RAB9AMAPTNPC1IL2JAK2 | |
| SCHEMBL11521969 | 0.85 | JAK2 (0.42) | RAB9AMAPTNPC1IL2SMN1; SMN2 | |
| SCHEMBL11521003 | 0.83 | KMO (0.45) | RAB9AMAPTNPC1IL2JAK2 | |
| SCHEMBL11526152 | 0.82 | RAB9A (0.42) | RAB9AMAPTGAANPSR1NPC1 | |
| SCHEMBL11524433 | 0.81 | MEN1 (0.45) | MAPTGAANPSR1NPC1ALDH1A1 | |
| SCHEMBL11525166 | 0.80 | SIRT2 (0.45) | RAB9AMAPTNPC1IL2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |