Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527873 | 0.89 | MAPK1 (0.40) | MT-CO2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11533788 | 0.86 | MT-CO2 (0.45) | MT-CO2PTGS2PTGS1PSEN1PSEN2 | |
| SCHEMBL11533787 | 0.85 | L3MBTL1 (0.40) | PTGS2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11528464 | 0.85 | AKR1C3 (0.46) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL11531372 | 0.74 | MT-CO2 (0.42) | MT-CO2PTGS2PTGS1PSEN1PSEN2 | |
| SCHEMBL11527230 | 0.72 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL11535068 | 0.71 | PTGS2 (0.48) | MT-CO2PTGS2PTGS1PSEN1PSEN2 | |
| SCHEMBL17926669 | 0.71 | HPGD (0.39) | HPGDTDP1MAPK1KARS1 | |
| SCHEMBL11013758 | 0.71 | HDAC1 (0.43) | MT-CO2PTGS2PTGS1PSEN1PSEN2 | |
| SCHEMBL11529076 | 0.70 | MT-CO2 (0.44) | MT-CO2PTGS2PTGS1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |