Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27233005 | 0.91 | GAA (0.54) | GAALMNAMAPTHTTMEN1 | |
| SCHEMBL8906782 | 0.86 | CASR (0.48) | GAACASRLMNAMAPTHTT | |
| SCHEMBL7995220 | 0.81 | GAA (0.59) | GAALMNAMAPTHTTMEN1 | |
| SCHEMBL6865356 | 0.80 | GAA (0.51) | GAALMNAMAPTHTTMEN1 | |
| SCHEMBL7875596 | 0.79 | GAA (0.51) | GAALMNAMAPTHTTMEN1 | |
| SCHEMBL11227972 | 0.78 | GAA (0.45) | GAACASRLMNAMAPTHTT | |
| SCHEMBL11692409 | 0.78 | GAA (0.50) | GAACASRLMNAMAPTHTT | |
| SCHEMBL11171692 | 0.78 | MEN1 (0.64) | GAALMNAMAPTHTTMEN1 | |
| SCHEMBL15329823 | 0.77 | ALOX5 (0.51) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL10620309 | 0.77 | ALDH1A1 (0.50) | GAALMNAMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132731-A | X-RAY CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |