Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535930 | 0.81 | GAA (0.40) | SMN1; SMN2KDM4EALDH1A1ATMGAA | |
| SCHEMBL11533860 | 0.80 | TP53 (0.36) | LMNASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL11532550 | 0.78 | NAAA (0.36) | LMNASMN1; SMN2KMT2AATMMEN1 | |
| SCHEMBL11530276 | 0.77 | CYP2C9 (0.43) | LMNASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL11530182 | 0.77 | KMT2A (0.34) | ALDH1A1KMT2AATMGAAPOLB | |
| SCHEMBL11526282 | 0.76 | L3MBTL1 (0.39) | KMT2AATMMEN1GAAPOLB | |
| SCHEMBL11527442 | 0.72 | GAA (0.33) | LMNASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL11529689 | 0.72 | HTT (0.34) | KMT2AATMGAAPOLBL3MBTL1 | |
| SCHEMBL11528816 | 0.71 | RECQL (0.41) | LMNAKDM4EALDH1A1KMT2AATM | |
| SCHEMBL9152870 | 0.68 | GAA (0.54) | KMT2AMEN1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |