Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533860 | 0.88 | TP53 (0.36) | CYP2C9NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11526282 | 0.87 | L3MBTL1 (0.39) | GAAKMT2AMEN1POLB | |
| SCHEMBL11532550 | 0.86 | NAAA (0.36) | CYP2C9NPSR1SMN1; SMN2GAAKMT2A | |
| SCHEMBL11529923 | 0.82 | ALDH1A1 (0.44) | NPSR1SMN1; SMN2KDM4EDHODHALDH1A1 | |
| SCHEMBL11532121 | 0.79 | GLO1 (0.45) | NPSR1SMN1; SMN2KDM4EDHODHALDH1A1 | |
| SCHEMBL11535930 | 0.79 | GAA (0.40) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11529689 | 0.77 | HTT (0.34) | GAAKMT2APOLB | |
| SCHEMBL11527436 | 0.77 | LMNA (0.41) | SMN1; SMN2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL11530182 | 0.74 | KMT2A (0.34) | ALDH1A1GAAKMT2APOLB | |
| SCHEMBL31036185 | 0.74 | CYP2C9 (0.43) | CYP2C9NPSR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |