Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530276 | 0.88 | CYP2C9 (0.43) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL11526282 | 0.82 | L3MBTL1 (0.39) | MEN1KMT2APOLBRECQLPKM | |
| SCHEMBL11527436 | 0.80 | LMNA (0.41) | TP53MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL11535930 | 0.75 | GAA (0.40) | POLBRECQLSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11529689 | 0.73 | HTT (0.34) | KMT2APOLBRECQLGAAEZH2 | |
| SCHEMBL7743874 | 0.72 | TP53 (0.49) | TP53MEN1KMT2APOLBMAPT | |
| SCHEMBL7547816 | 0.72 | TP53 (0.49) | TP53MEN1KMT2APOLBMAPT | |
| SCHEMBL11530182 | 0.71 | KMT2A (0.34) | KMT2APOLBRECQLALDH1A1GAA | |
| SCHEMBL11528816 | 0.70 | RECQL (0.41) | MEN1KMT2APOLBMAPTRECQL | |
| SCHEMBL7707530 | 0.70 | NAAA (0.41) | MEN1KMT2APOLBMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |