Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530182 | 0.84 | KMT2A (0.34) | GAAPOLBRECQLL3MBTL1ATM | |
| SCHEMBL11526282 | 0.83 | L3MBTL1 (0.39) | GAAPOLBRECQLL3MBTL1ATM | |
| SCHEMBL11527436 | 0.81 | LMNA (0.41) | GAAPOLBL3MBTL1ATMALDH1A1 | |
| SCHEMBL8894378 | 0.81 | GAA (0.50) | GAAPOLBL3MBTL1EZH2ALDH1A1 | |
| SCHEMBL11530276 | 0.79 | CYP2C9 (0.43) | GAAPOLBALDH1A1KDM4ENPC1 | |
| SCHEMBL11529689 | 0.79 | HTT (0.34) | GAAPOLBRECQLL3MBTL1ATM | |
| SCHEMBL11528816 | 0.78 | RECQL (0.41) | GAAPOLBRECQLL3MBTL1ATM | |
| SCHEMBL3295977 | 0.76 | RECQL (0.57) | GAAPOLBRECQLL3MBTL1ATM | |
| SCHEMBL11533860 | 0.75 | TP53 (0.36) | GAAPOLBRECQLL3MBTL1ATM | |
| SCHEMBL9154782 | 0.71 | GAA (0.52) | GAAPOLBRECQLL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |