Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527520 | 0.85 | OPRK1 (0.38) | ELANEMC4RGAAACHEHTT | |
| SCHEMBL11177639 | 0.80 | CTSL (0.45) | MC4RGAASIGMAR1 | |
| SCHEMBL14354626 | 0.78 | GAA (0.39) | ELANECTSGPRTN3MC4RGAA | |
| SCHEMBL11233987 | 0.78 | MC4R (0.36) | ELANEMC4RGAAACHESIGMAR1 | |
| SCHEMBL7771026 | 0.77 | TDP1 (0.40) | MC4RGAASIGMAR1MEN1KMT2A | |
| SCHEMBL10895930 | 0.77 | CYP2C19 (0.39) | ELANEMC4RGAAHTTTSHR | |
| SCHEMBL39509 | 0.76 | KMT2A (0.44) | ELANEGAAACHESIGMAR1TSHR | |
| SCHEMBL1309638 | 0.76 | GAA (0.41) | ELANEMC4RGAAACHELMNA | |
| SCHEMBL11088315 | 0.76 | MEN1 (0.41) | ELANEMC4RGAAACHELMNA | |
| SCHEMBL11173679 | 0.75 | DRD2 (0.34) | ELANEMC4RGAAACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177186-A | 4-SILOXY-DERIVATIVES OF STERICALLY HINDERED PIPERIDINES | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |