Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527474 | 0.85 | ELANE (0.38) | OPRK1MC4RGAAELANEACHE | |
| SCHEMBL11524799 | 0.81 | UBE2M (0.36) | TSHRSIGMAR1 | |
| SCHEMBL11527319 | 0.81 | LMNA (0.31) | GAATSHRKMT2ASIGMAR1 | |
| SCHEMBL11525444 | 0.80 | LMNA (0.36) | GAAHTTSMN1; SMN2TSHRKMT2A | |
| SCHEMBL11177639 | 0.78 | CTSL (0.45) | MC4RGAACYP3A4CYP2C9SIGMAR1 | |
| SCHEMBL11233987 | 0.75 | MC4R (0.36) | OPRK1MC4RGAAELANECYP3A4 | |
| SCHEMBL14354626 | 0.75 | GAA (0.39) | MC4RGAAELANEACHEHTT | |
| SCHEMBL11527304 | 0.74 | KMT2A (0.42) | GAACYP3A4HTTTSHRAMPD2 | |
| SCHEMBL10895930 | 0.74 | CYP2C19 (0.39) | MC4RGAAELANECYP3A4CYP2C9 | |
| SCHEMBL1309638 | 0.73 | GAA (0.41) | OPRK1MC4RGAAELANEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177186-A | 4-SILOXY-DERIVATIVES OF STERICALLY HINDERED PIPERIDINES | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |