Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354626 | 0.85 | GAA (0.39) | MC4RGAAELANEACHETSHR | |
| SCHEMBL11171764 | 0.83 | ALOX15 (0.35) | MC4RGAAELANEACHETSHR | |
| SCHEMBL9421827 | 0.80 | TSHR (0.41) | GAATSHRKMT2AMEN1AMPD2 | |
| SCHEMBL11177639 | 0.79 | CTSL (0.45) | MC4RGAASIGMAR1CYP3A4CYP2C9 | |
| SCHEMBL11527474 | 0.78 | ELANE (0.38) | MC4RGAAELANEACHETSHR | |
| SCHEMBL315331 | 0.76 | TSHR (0.43) | MC4RGAATSHRKMT2AMEN1 | |
| SCHEMBL315332 | 0.76 | TSHR (0.43) | MC4RGAATSHRKMT2AMEN1 | |
| SCHEMBL11527520 | 0.75 | OPRK1 (0.38) | MC4RGAAELANEACHETSHR | |
| SCHEMBL10895930 | 0.75 | CYP2C19 (0.39) | MC4RGAAELANETSHRKMT2A | |
| SCHEMBL39509 | 0.74 | KMT2A (0.44) | GAAELANEACHETSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015237-B1 | HOMO- AND COPOLYMERS OF VINYL ETHERS OF POLYALKYLPIPERIDINOLS AND THEIR UTILISATION AS STABILIZERS FOR PLASTICS | CIBA-GEIGY AG (CH) | 1982-12-15 | — | — | EP | disclosed |
| US-4360675-A | Homopolymers and copolymers of vinyl ethers of polyalkylpiperidinols and their use as stabilizers for plastics | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4311820-A | Homopolymers and copolymers of vinyl ethers of polyalkylpiperidinols and their use as stabilizers for plastics | CIBA-GEIGY CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| EP-0015237-A1 | Homo- and copolymers of vinyl ethers of polyalkylpiperidinols and their utilisation as stabilizers for plastics | CIBA-GEIGY AG (CH) | 1980-09-03 | — | — | EP | disclosed |