Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254773 | 0.88 | CES1 (0.65) | TSHRLMNAGAAKMT2APKM | |
| Methyl Carbamate SCHEMBL28555184 | 0.88 | POLB (0.60) | TSHRLMNAGAAKMT2APKM | |
| Methylamine SCHEMBL29169653 | 0.87 | TSHR (0.60) | TSHRLMNAGAAKMT2APKM | |
| Methyl Carbamate SCHEMBL28555185 | 0.82 | CES2 (0.57) | TSHRLMNAGAAKMT2APKM | |
| SCHEMBL7297660 | 0.82 | TSHR (0.55) | TSHRLMNAGAAKMT2APKM | |
| SCHEMBL30849215 | 0.82 | PARP10 (0.42) | LMNAGAAKMT2AMAPTALDH1A1 | |
| SCHEMBL5389258 | 0.81 | MAPK1 (0.63) | TSHRLMNAKMT2APKMCES1 | |
| SCHEMBL254774 | 0.81 | CES1 (0.70) | TSHRLMNAKMT2ACES1MAPT | |
| SCHEMBL11527673 | 0.81 | CES1 (0.57) | TSHRLMNAGAAKMT2APKM | |
| SCHEMBL4399328 | 0.81 | ALDH1A1 (0.63) | TSHRLMNAGAAKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144333-A | Monocyclic beta-lactams with antibacterial activity | SMITHKLINE CORPORATION (US) | 1979-03-13 | — | — | US | claimed |
| CN-111825611-B | 4(1H) -quinovone derivatives and uses thereof | 刘扶东 | 2022-09-09 | — | — | CN | disclosed |
| EP-2590978-B1 | CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY | FOB SYNTHESIS INC (US) | 2017-09-20 | — | — | EP | disclosed |
| CN-101535258-B | ether derivatives dual modulators of the 5HT2A and D3 receptors | HOFFMANN LA ROCHE | 2012-12-05 | — | — | CN | disclosed |