Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27943154 | 0.82 | GABRA1 (0.35) | GABRA1GABRB2MGLLMAPTNPSR1 | |
| SCHEMBL115194 | 0.80 | MGLL (0.42) | GABRA1GABRB2MGLLMAPTNPSR1 | |
| SCHEMBL21383150 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2MGLLMAPTNPSR1 | |
| Naphthalene SCHEMBL28055830 | 0.75 | MGLL (0.38) | GABRA1GABRB2MGLLMAPTNPSR1 | |
| SCHEMBL8375453 | 0.73 | KMT2A (0.41) | MAPTL3MBTL1ALDH1A1HTT | |
| SCHEMBL20637440 | 0.73 | GABRA1 (0.42) | GABRA1GABRB2MGLLMAPTNPSR1 | |
| SCHEMBL11128898 | 0.72 | MGLL (0.36) | GABRA1GABRB2MGLLMAPTTP53 | |
| SCHEMBL27853813 | 0.72 | GABRA1 (0.34) | GABRA1GABRB2MGLLMAPTNPSR1 | |
| Methylene Chloride SCHEMBL27614482 | 0.71 | GABRA1 (0.50) | GABRA1GABRB2MGLLMAPTNPSR1 | |
| SCHEMBL28853525 | 0.71 | GABRA1 (0.41) | GABRA1GABRB2MGLLMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132725-A | Substituted 3,1-benzazasilin-4-ones | SANDOZ, INC. (US) | 1979-01-02 | — | — | US | disclosed |