SCHEMBL8375453

SCHEMBL8375453

CCc1ccccc1[SiH](Cl)CN1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
POLB P06746 2/20 0.41
ALDH1A1 P00352 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 3/20 0.38
HRH3 Q9Y5N1 3/20 0.36
MAPT P10636 2/20 0.36
SIGMAR1 Q99720 1/20 0.35
ALOX5 P09917 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11528209 0.73 GABRA1 (0.37) ALDH1A1L3MBTL1MAPTHTT
SCHEMBL13469225 0.72 ALDH1A1 (0.61) KMT2AMEN1POLBALDH1A1KDM4E
SCHEMBL27943154 0.72 GABRA1 (0.35) POLBL3MBTL1MAPTHTT
SCHEMBL115194 0.70 MGLL (0.42) ALDH1A1L3MBTL1MAPT
SCHEMBL1964500 0.70 ALDH1A1 (0.58) KMT2AMEN1POLBALDH1A1L3MBTL1
SCHEMBL21383150 0.69 GABRA1 (0.39) ALDH1A1L3MBTL1MAPT
SCHEMBL6514775 0.66 KEAP1 (0.53) KMT2AL3MBTL1MAPTALOX5
SCHEMBL13347750 0.66 ALDH1A1 (0.53) KMT2AMEN1POLBALDH1A1KDM4E
Naphthalene SCHEMBL28055830 0.66 MGLL (0.38) ALDH1A1L3MBTL1KDM4EMAPT
Hydrochloric Acid SCHEMBL29156848 0.65 KEAP1 (0.52) KMT2AL3MBTL1MAPTALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0902031-A2 Aminosilanes and method of preparation DOW CORNING CORPORATION (US) 1999-03-17 EP claimed
EP-4466300-A1 A THERMOSET COMPOSITE COMPRISING A CROSSLINKED IMIDE EXTENDED COMPOUND Rogers Corporation (US) 2024-11-27 EP disclosed
US-20240203624-A1 Y-TYPE HEXAFERRITE, METHOD OF MANUFACTURE, AND USES THEREOF ROGERS CORP (US) 2024-06-20 US disclosed
WO-2024118317-A1 Y-TYPE HEXAFERRITE, METHOD OF MANUFACTURE, AND USES THEREOF ROGERS CORPORATION (US) 2024-06-06 WO disclosed
US-20230399237-A1 Y-TYPE HEXAFERRITE, METHOD OF MANUFACTURE, AND USES THEREOF ROGERS CORPORATION 2023-12-14 US disclosed
WO-2023239594-A1 Y-TYPE HEXAFERRITE, METHOD OF MANUFACTURE, AND USES THEREOF ROGERS CORPORATION (US) 2023-12-14 WO disclosed
US-20230242709-A1 THERMOSET COMPOSITE COMPRISING A CROSSLINKED IMIDE EXTENDED COMPOUND ROGERS CORPORATION 2023-08-03 US disclosed
WO-2023141035-A1 A THERMOSET COMPOSITE COMPRISING A CROSSLINKED IMIDE EXTENDED COMPOUND ROGERS CORPORATION (US) 2023-07-27 WO disclosed
US-11198263-B2 Melt processable thermoplastic composite comprising a multimodal dielectric filler ROGERS CORPORATION (US) 2021-12-14 US disclosed
US-20200270413-A1 LOW LOSS DIELECTRIC COMPOSITE COMPRISING A HYDROPHOBIZED FUSED SILICA JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2020-08-27 US disclosed
WO-2019183192-A1 MELT PROCESSABLE THERMOPLASTIC COMPOSITE COMPRISING A MULTIMODAL DIELECTRIC FILLER ROGERS CORPORATION (US) 2019-09-26 WO disclosed
US-20190291364-A1 MELT PROCESSABLE THERMOPLASTIC COMPOSITE COMPRISING A MULTIMODAL DIELECTRIC FILLER JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2019-09-26 US disclosed
EP-0902031-A2 Aminosilanes and method of preparation DOW CORNING CORPORATION (US) 1999-03-17 EP disclosed