SCHEMBL115194

SCHEMBL115194

CCc1ccccc1[SiH](Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.42
GABRA1 P14867 4/20 0.41
GABRB2 P47870 4/20 0.41
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TP53 P04637 1/20 0.35
CYP2D6 P10635 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CSNK2A3 Q8NEV1 1/20 0.33
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
CTSB P07858 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL28055830 0.94 MGLL (0.38) MGLLGABRA1GABRB2MAPTNPSR1
SCHEMBL11128898 0.90 MGLL (0.36) MGLLGABRA1GABRB2MAPTTP53
SCHEMBL21383150 0.84 GABRA1 (0.39) MGLLGABRA1GABRB2MAPTNPSR1
SCHEMBL3482512 0.82 LIPG (0.33) MGLLMAPTALDH1A1GAALMNA
SCHEMBL11528209 0.80 GABRA1 (0.37) MGLLGABRA1GABRB2MAPTNPSR1
SCHEMBL27943154 0.79 GABRA1 (0.35) MGLLGABRA1GABRB2MAPTNPSR1
SCHEMBL3482161 0.79 LIPG (0.43) CYP2D6
SCHEMBL1262668 0.78 ALDH1A1 (0.39) ALDH1A1
SCHEMBL20637440 0.78 GABRA1 (0.42) MGLLGABRA1GABRB2MAPTNPSR1
SCHEMBL15209481 0.78 HTT (0.33) MAPTNPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112898757-A Method for preparing transparent toughened polylactic acid material based on silicone rubber microspheres 杭州卓普新材料科技有限公司 2021-06-04 CN claimed
CN-110305457-B Preparation method of transparent toughened polylactic acid material 杭州卓普新材料科技有限公司 2021-04-30 CN claimed
CN-110305457-A Preparation method of transparent toughened polylactic acid material 杭州卓普新材料科技有限公司 2019-10-08 CN claimed
CN-103408758-B A kind of preparation method of ethyl phenyl silicone oil JIANGSU UNIVERSITY (CN) 2015-10-28 CN claimed
CN-103408758-A Preparation method of ethyl phenyl silicone oil UNIV JIANGSU 2013-11-27 CN claimed
CN-101880516-B Low free MDI monomer bicomponent solvent-free GUANGDONG GOOD CHEMICAL SCIENCE & TECHNOLOGY CO LTD 2013-01-30 CN claimed
CN-101307126-B MDI trimer curing agent and method for preparing same WUHAN SHIQUANXING POLYURETHANE TECHNOLOGY CO LTD 2012-05-30 CN claimed
CN-101307127-B Polyurethane curing agent with low free MDI monomer and method for preparing same WUHAN SHIQUANXING DECORATIVE PAINT CO LTD 2010-12-01 CN claimed
CN-101880516-A Low free MDI monomer bicomponent solvent-free GUANGDONG GOOD CHEMICAL SCIENCE & TECHNOLOGY CO LTD 2010-11-10 CN claimed
CN-101307128-B High-compatibility MDI and TDI mixed trimer curing agent and method for preparing same WUHAN SHIQUANXING DECORATIVE PAINT CO LTD 2010-08-18 CN claimed
CN-101307127-A Polyurethane curing agent with low free MDI monomer and method for preparing same WUHAN SHIQUANXING DECORATIVE P (CN) 2008-11-19 CN claimed
CN-101307126-A MDI trimer curing agent and method for preparing same WUHAN SHIQUANXING DECORATIVE P (CN) 2008-11-19 CN claimed
CN-101307128-A High-compatibility MDI and TDI mixed trimer curing agent and method for preparing same WUHAN SHIQUANXING DECORATIVE P (CN) 2008-11-19 CN claimed
US-5286891-A Hydrolysis of chloro-termianted polysilane SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-02-15 US claimed
EP-0231497-A1 Silicone resist materials containing polysiloxanes KABUSHIKI KAISHA TOSHIBA (JP) 1987-08-12 EP claimed
EP-4306530-B1 SILANE-CONTAINING CONDENSED CYCLIC DIPEPTIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND METHOD FOR PRODUCING POLYPEPTIDE COMPOUND USING SAME CHUBU UNIV EDUCATIONAL FOUNDATION (JP) 2026-04-01 EP disclosed
US-20240182517-A1 SILANE-CONTAINING CONDENSED CYCLIC DIPEPTIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND METHOD FOR PRODUCING POLYPEPTIDE COMPOUND USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2024-06-06 US disclosed
US-4269894-A AS BINDERS FOR THE MULTILAYERED INSULATION; IMPREGNATING WITH A VARNISH OF EPOXY-ISOCYANATE RESIN; WATERPROOFING HITACHI, LTD. (JP) 1981-05-26 US disclosed
EP-0012566-A1 Electric windings and production thereof Hitachi, Ltd. (JP) 1980-06-25 EP disclosed
US-3987061-A METAL COMPLEXING AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182517-A1 SILANE-CONTAINING CONDENSED CYCLIC DIPEPTIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND METHOD FOR PRODUCING POLYPEPTIDE COMPOUND USING SAME VIP, NGLY1, NPR1 MGLL 4357/4885GABRA1 2466/4885GABRB2 3190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.