Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329126 | 0.82 | MEN1 (0.44) | PTGER1PTGER4PTGER3PTGER2KMO | |
| SCHEMBL11318153 | 0.82 | MEN1 (0.44) | PTGER1PTGER4PTGER3PTGER2KMO | |
| SCHEMBL11529950 | 0.80 | PTGER4 (0.48) | PTGER1PTGER4PTGER3PTGER2KMO | |
| Water SCHEMBL11531305 | 0.79 | PTGER4 (0.47) | PTGER1PTGER4PTGER3PTGER2KMO | |
| SCHEMBL11700214 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPK1TDP1HNF4AHDAC8 | |
| SCHEMBL11530624 | 0.76 | ACMSD (0.51) | PTGER1PTGER4PTGER3PTGER2KMO | |
| SCHEMBL11533440 | 0.75 | KMO (0.38) | PTGER1PTGER4PTGER3PTGER2KMO | |
| SCHEMBL11568765 | 0.72 | ACMSD (0.49) | ALDH1A1MAPK1TDP1ACMSDHNF4A | |
| SCHEMBL11530588 | 0.72 | ACMSD (0.49) | ALDH1A1MAPK1TDP1ACMSDHNF4A | |
| Water SCHEMBL11409301 | 0.71 | HNF4A (0.47) | ALDH1A1MAPK1TDP1HNF4AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147728-A | Disubstituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4064176-A | Di-substituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1977-12-20 | — | — | US | disclosed |
| US-4045414-A | New di-substituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1977-08-30 | — | — | US | disclosed |