Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528277 | 0.75 | PTGER1 (0.43) | KMOPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL17720739 | 0.70 | PDE4B (0.44) | BACE1EGFR | |
| SCHEMBL8145252 | 0.68 | BACE1 (0.50) | BACE1EGFRHNF4A | |
| SCHEMBL11530624 | 0.67 | ACMSD (0.51) | KMOPTGER1PTGER4PTGER3PTGER2 | |
| Hydrogen Sulfide SCHEMBL27805768 | 0.67 | L3MBTL1 (0.36) | BACE1THRATHRB | |
| SCHEMBL9704212 | 0.66 | PTGER4 (0.49) | KMOPTGER1PTGER4PTGER3PTGER2 | |
| Biphenyl SCHEMBL11409296 | 0.66 | ALDH1A1 (0.44) | KMO | |
| Glyoxylate SCHEMBL6308341 | 0.65 | KMO (0.52) | KMOPTGER1PTGER4PTGER3PTGER2 | |
| Formic Acid SCHEMBL27890706 | 0.65 | KMO (0.58) | KMOPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL28891243 | 0.65 | FABP4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147728-A | Disubstituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1979-04-03 | — | — | US | disclosed |